P4872
Anti-Potassium Channel KCa1.1, (BKCa) (1184-1200)(Large-conductance Ca2+-activated Potassium Channel) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
别名:
Anti-KCNMA1, Anti-MAXI K+
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, rat, mouse
technique(s)
western blot: 1:500 using rat brain membranes
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... KCNMA1(3778)
mouse ... Kcnma1(16531)
rat ... Kcnma1(83731)
Immunogen
synthetic peptide corresponding to amino acid residues 1184-1200 of mouse KCa1.1. Sequence homology with rat is identical. Human, bovine, chicken, and dog are 16/17 residues identical.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Immunocytochemistry (1 paper)
Physical form
Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.025% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
T J Heppner et al.
The American journal of physiology, 273(1 Pt 1), C110-C117 (1997-07-01)
The goal of this study was to examine the role of large conductance Ca(2+)-activated K+ channels in the regulation of cell excitability in urinary bladder smooth muscle from the guinea pig. Ca(2+)-activated K+ channels were studied with single-channel recording techniques
H G Knaus et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 16(3), 955-963 (1996-02-01)
Tissue expression and distribution of the high-conductance Ca(2+)-activated K+ channel Slo was investigated in rat brain by immunocytochemistry, in situ hybridization, and radioligand binding using the novel high-affinity (Kd 22 pM) ligand [3H]iberiotoxin-D19C ([3H]IbTX-D19C), which is an analog of the
Dahis Manzanares et al.
American journal of physiology. Lung cellular and molecular physiology, 306(5), L453-L462 (2014-01-15)
Effective mucociliary clearance (MCC) depends in part on adequate airway surface liquid (ASL) volume to maintain an appropriate periciliary fluid height that allows normal ciliary activity. Apically expressed large-conductance, Ca(2+)-activated, and voltage-dependent K(+) (BK) channels provide an electrochemical gradient for
Maj Rabjerg et al.
PloS one, 10(4), e0122992-e0122992 (2015-04-08)
Ca2+-activated K+ channels have been implicated in cancer cell growth, metastasis, and tumor angiogenesis. Here we hypothesized that high mRNA and protein expression of the intermediate-conductance Ca2+-activated K+ channel, KCa3.1, is a molecular marker of clear cell Renal Cell Carcinoma
Dahis Manzanares et al.
The Journal of biological chemistry, 286(22), 19830-19839 (2011-04-02)
Large conductance, Ca(2+)-activated, and voltage-dependent K(+) (BK) channels control a variety of physiological processes in nervous, muscular, and renal epithelial tissues. In bronchial airway epithelia, extracellular ATP-mediated, apical increases in intracellular Ca(2+) are important signals for ion movement through the
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