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Merck
CN

P4898

Sigma-Aldrich

Phe-Met-Arg-Phe amide

≥95% (HPLC)

别名:

FMRF amide, Molluscan cardioexcitatory neuropeptide

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关于此项目

经验公式(希尔记法):
C29H42N8O4S
化学文摘社编号:
分子量:
598.76
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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方案

≥95% (HPLC)

表单

powder

组成

Peptide content, ~65%

技术

mass spectrometry (MS): suitable

颜色

white

储存温度

−20°C

SMILES字符串

CSCCC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc2ccccc2)C(N)=O

InChI

1S/C29H42N8O4S/c1-42-16-14-23(35-26(39)21(30)17-19-9-4-2-5-10-19)28(41)36-22(13-8-15-34-29(32)33)27(40)37-24(25(31)38)18-20-11-6-3-7-12-20/h2-7,9-12,21-24H,8,13-18,30H2,1H3,(H2,31,38)(H,35,39)(H,36,41)(H,37,40)(H4,32,33,34)

InChI key

WCSPDMCSKYUFBX-UHFFFAOYSA-N

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tamás Röszer et al.
Brain, behavior and evolution, 63(1), 23-33 (2003-12-16)
The anatomical and functional relationship between neurons expressing nitric oxide (NO) synthase and molluscan cardioexcitatory (FMRFamide)-like neuropeptides was studied in the central ganglia of Helix lucorum (Pulmonata, Gastropoda), applying NADPHdiaphorase (NADPHd) histochemistry to visualize NO synthase and immunocytochemistry to demonstrate
Tamás Roszer et al.
Cell and tissue research, 325(3), 567-575 (2006-04-14)
The possible involvement of the L-arginine-containing Phe-met-arg-phe (FMRF)-amide (FMRFa) in neuronal nitric oxide (NO) biosynthesis was studied in a gastropod species. We found NADPH-diaphorase-positive neurons and FMRFa-containing fibers in close proximity in the enteric nervous system. Administration of L-arginine and
Abdesslam Chrachri et al.
The European journal of neuroscience, 17(3), 526-536 (2003-02-13)
The effects of the neuropeptide FMRFa on spontaneous excitatory postsynaptic currents (sEPSCs) and inhibitory postsynaptic currents (sIPSCs), as well as on evoked EPSCs and IPSCs, in two types of neurons within the central optic lobe of cuttlefish were examined using
D A Price et al.
Science (New York, N.Y.), 197(4304), 670-671 (1977-08-12)
A cardioexcitatory substance from ganglia of the clam Macrocallista nimbosa, formerly designated peak C, is the tetrapeptide amide Phe-Met-Arg-Phe-NH2. Its structure was determined by the combined use of Edman dansyl degradation and tryptic digestion. The structure was confirmed by synthesis.
Louise E Atkinson et al.
PLoS pathogens, 9(2), e1003169-e1003169 (2013-03-08)
Restrictions on nematicide usage underscore the need for novel control strategies for plant pathogenic nematodes such as Globodera pallida (potato cyst nematode) that impose a significant economic burden on plant cultivation activities. The nematode neuropeptide signalling system is an attractive

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