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Merck
CN

P4898

Phe-Met-Arg-Phe amide

≥95% (HPLC)

别名:

FMRF amide, Molluscan cardioexcitatory neuropeptide

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经验公式(希尔记法):
C29H42N8O4S
化学文摘社编号:
分子量:
598.76
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C29H42N8O4S/c1-42-16-14-23(35-26(39)21(30)17-19-9-4-2-5-10-19)28(41)36-22(13-8-15-34-29(32)33)27(40)37-24(25(31)38)18-20-11-6-3-7-12-20/h2-7,9-12,21-24H,8,13-18,30H2,1H3,(H2,31,38)(H,35,39)(H,36,41)(H,37,40)(H4,32,33,34)

SMILES string

CSCCC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc2ccccc2)C(N)=O

InChI key

WCSPDMCSKYUFBX-UHFFFAOYSA-N

assay

≥95% (HPLC)

form

powder

composition

Peptide content, ~65%

technique(s)

mass spectrometry (MS): suitable

color

white

storage temp.

−20°C

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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Tamás Roszer et al.
Cell and tissue research, 325(3), 567-575 (2006-04-14)
The possible involvement of the L-arginine-containing Phe-met-arg-phe (FMRF)-amide (FMRFa) in neuronal nitric oxide (NO) biosynthesis was studied in a gastropod species. We found NADPH-diaphorase-positive neurons and FMRFa-containing fibers in close proximity in the enteric nervous system. Administration of L-arginine and
Tamás Röszer et al.
Brain, behavior and evolution, 63(1), 23-33 (2003-12-16)
The anatomical and functional relationship between neurons expressing nitric oxide (NO) synthase and molluscan cardioexcitatory (FMRFamide)-like neuropeptides was studied in the central ganglia of Helix lucorum (Pulmonata, Gastropoda), applying NADPHdiaphorase (NADPHd) histochemistry to visualize NO synthase and immunocytochemistry to demonstrate
Abdesslam Chrachri et al.
The European journal of neuroscience, 17(3), 526-536 (2003-02-13)
The effects of the neuropeptide FMRFa on spontaneous excitatory postsynaptic currents (sEPSCs) and inhibitory postsynaptic currents (sIPSCs), as well as on evoked EPSCs and IPSCs, in two types of neurons within the central optic lobe of cuttlefish were examined using
Daniel Kueh et al.
The Journal of experimental biology, 215(Pt 12), 2108-2116 (2012-05-25)
The heart excitor (HE) motor neuron in the leech Hirudo releases acetylcholine (ACh) and a peptide, FMRFamide, to regulate the contractile activity of the heart tube and associated side vessels. Consistent with Dale's principle, it was assumed that both neurotransmitters
Nelly A Odintsova et al.
Journal of molecular histology, 43(4), 449-459 (2012-06-08)
Using immunofluorescence phenotyping, the expression of αvβ3-like integrin was examined during neuronal and muscle differentiation in cell cultures derived from trochophore larvae of the mussel Mytilus trossulus. We have demonstrated that some mussel cells grown on fibronectin in vitro express

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