跳转至内容
Merck
CN

P5865

Rp-8-PIP-cAMPS

≥98% (HPLC), solid

别名:

8-Piperidinoadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer sodium salt

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C15H20N6O5PSNa
分子量:
450.39
UNSPSC Code:
41106305
PubChem Substance ID:
329820237
MDL number:
MFCD04037244

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

InChI

1S/C15H21N6O5PS.Na/c16-12-9-13(18-7-17-12)21(15(19-9)20-4-2-1-3-5-20)14-10(22)11-8(25-14)6-24-27(23,28)26-11;/h7-8,10-11,14,22H,1-6H2,(H,23,28)(H2,16,17,18);/q;+1/p-1/t8-,10-,11-,14-,27-;/m1./s1

SMILES string

[Na+].Nc1ncnc2n([C@@H]3O[C@@H]4CO[P@@]([O-])(=S)O[C@H]4[C@H]3O)c(nc12)N5CCCCC5

InChI key

ILHHHOJPVCBSBI-RYTXRTGRSA-M

assay

≥98% (HPLC)

form

solid

mol wt

apparent mol wt 457.40

storage temp.

−20°C

Biochem/physiol Actions

Site-selective, lipophilic analogue of the phosphodiesterase-stable protein kinase A inhibitor Rp-cAMPS (Prod. No. A-165).

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
096K1415
116K1158
091K1156

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

D Ogreid et al.
European journal of biochemistry, 221(3), 1089-1094 (1994-05-01)
8-Piperidino-cAMP has been shown to bind with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI) whereas it is partially excluded from the homologous site (AII) of isozyme II [Ogreid, D., Ekanger, R.
Haiyan Liu et al.
Molecular pharmacology, 76(6), 1290-1301 (2009-09-08)
Bovine adrenal zona fasciculata (AZF) cells express bTREK-1 K+ channels whose inhibition by cAMP is coupled to membrane depolarization and cortisol secretion through complex signaling mechanisms. cAMP analogs with substitutions in the 6 position of the adenine ring selectively activate
Amod Godbole et al.
Nature communications, 8(1), 443-443 (2017-09-07)
A new paradigm of G-protein-coupled receptor (GPCR) signaling at intracellular sites has recently emerged, but the underlying mechanisms and functional consequences are insufficiently understood. Here, we show that upon internalization in thyroid cells, endogenous TSH receptors traffic retrogradely to the

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持