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Merck
CN

P6386

L-α-磷脂酰乙醇胺 来源于鸡蛋黄

Type III, 10 mg/mL in chloroform, ≥97%, solution

别名:

1,2-二酰基-sn-甘油-3-磷酸乙醇胺, L-α-脑磷脂

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关于此项目

化学文摘社编号:
39382-08-6
EC 号:
200-663-8
MDL编号:
MFCD00146357
UNSPSC代码:
51191904
NACRES:
NA.25

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生物来源

egg yolk

质量水平

200

类型

Type III

方案

≥97%

表单

solution

浓度

10 mg/mL in chloroform

官能团

phospholipid

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

SMILES字符串

[P](=O)(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCC)(OCCN)O

InChI

1S/C40H80NO8P/c1-3-5-7-9-11-13-15-17-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41)36-46-39(42)32-30-28-26-24-22-16-14-12-10-8-6-4-2/h38H,3-37,41H2,1-2H3,(H,44,45)/t38-/m1/s1

InChI key

NJGIRBISCGPRPF-KXQOOQHDSA-N

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免责声明

制备时纯度为 98-99%。该溶液暴露在室温下每天可分解 0.3-0.5%。

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

易制毒化学品（2类）
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000463206
0000463204
0000463204
0000463206
0000403687

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Faraz Quazi et al.
The Journal of biological chemistry, 288(48), 34414-34426 (2013-10-08)
ABCA1, ABCA7, and ABCA4 are members of the ABCA subfamily of ATP-binding cassette transporters that share extensive sequence and structural similarity. Mutations in ABCA1 cause Tangier disease characterized by defective cholesterol homeostasis and high density lipoprotein (HDL) deficiency. Mutations in
Christin Stegemann et al.
Circulation, 129(18), 1821-1831 (2014-03-14)
The bulk of cardiovascular disease risk is not explained by traditional risk factors. Recent advances in mass spectrometry allow the identification and quantification of hundreds of lipid species. Molecular lipid profiling by mass spectrometry may improve cardiovascular risk prediction. Lipids
Heike Anders et al.
International journal of systematic and evolutionary microbiology, 64(Pt 4), 1264-1270 (2014-01-16)
A strictly aerobic, thermophilic, moderately acidophilic, non-spore-forming bacterium, strain P373(T), was isolated from geothermally heated soil at Waikite, New Zealand. Cells were filamentous rods, 0.2-0.4 µm in diameter and grew in chains up to 80 µm in length. On the
Haim Haviv et al.
The Journal of biological chemistry, 288(14), 10073-10081 (2013-02-23)
Membrane proteins interact with phospholipids either via an annular layer surrounding the transmembrane segments or by specific lipid-protein interactions. Although specifically bound phospholipids are observed in many crystal structures of membrane proteins, their roles are not well understood. Na,K-ATPase is
Nobuo N Noda et al.
EMBO reports, 14(2), 206-211 (2012-12-15)
Atg12 is conjugated to Atg5 through enzymatic reactions similar to ubiquitination. The Atg12-Atg5 conjugate functions as an E3-like enzyme to promote lipidation of Atg8, whereas lipidated Atg8 has essential roles in both autophagosome formation and selective cargo recognition during autophagy.
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实验方案

LC/MS Analysis of Phospholipids in Milk on Asc

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

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