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安全信息

P6386

Sigma-Aldrich

L-α-磷脂酰乙醇胺 来源于鸡蛋黄

Type III, 10 mg/mL in chloroform, ≥97%, solution

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别名:
1,2-二酰基-sn-甘油-3-磷酸乙醇胺, L-α-脑磷脂
CAS号:
EC 号:
MDL编号:
NACRES:
NA.25

生物来源

egg yolk

质量水平

类型

Type III

检测方案

≥97%

形式

solution

浓度

10 mg/mL in chloroform

官能团

phospholipid

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

InChI

1S/C40H80NO8P/c1-3-5-7-9-11-13-15-17-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41)36-46-39(42)32-30-28-26-24-22-16-14-12-10-8-6-4-2/h38H,3-37,41H2,1-2H3,(H,44,45)/t38-/m1/s1

InChI key

NJGIRBISCGPRPF-KXQOOQHDSA-N

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注意

制备时纯度为 98-99%。该溶液暴露在室温下每天可分解 0.3-0.5%。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

易制毒化学品(2类)
危险化学品

分析证书(COA)

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Faraz Quazi et al.
The Journal of biological chemistry, 288(48), 34414-34426 (2013-10-08)
ABCA1, ABCA7, and ABCA4 are members of the ABCA subfamily of ATP-binding cassette transporters that share extensive sequence and structural similarity. Mutations in ABCA1 cause Tangier disease characterized by defective cholesterol homeostasis and high density lipoprotein (HDL) deficiency. Mutations in
Christin Stegemann et al.
Circulation, 129(18), 1821-1831 (2014-03-14)
The bulk of cardiovascular disease risk is not explained by traditional risk factors. Recent advances in mass spectrometry allow the identification and quantification of hundreds of lipid species. Molecular lipid profiling by mass spectrometry may improve cardiovascular risk prediction. Lipids
Heike Anders et al.
International journal of systematic and evolutionary microbiology, 64(Pt 4), 1264-1270 (2014-01-16)
A strictly aerobic, thermophilic, moderately acidophilic, non-spore-forming bacterium, strain P373(T), was isolated from geothermally heated soil at Waikite, New Zealand. Cells were filamentous rods, 0.2-0.4 µm in diameter and grew in chains up to 80 µm in length. On the
Haim Haviv et al.
The Journal of biological chemistry, 288(14), 10073-10081 (2013-02-23)
Membrane proteins interact with phospholipids either via an annular layer surrounding the transmembrane segments or by specific lipid-protein interactions. Although specifically bound phospholipids are observed in many crystal structures of membrane proteins, their roles are not well understood. Na,K-ATPase is
Manoj K Rathinaswamy et al.
eLife, 10 (2021-03-05)
Class I Phosphoinositide 3-kinases (PI3Ks) are master regulators of cellular functions, with the class IB PI3K catalytic subunit (p110γ) playing key roles in immune signalling. p110γ is a key factor in inflammatory diseases and has been identified as a therapeutic

实验方案

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

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