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Merck
CN

P6997

Sigma-Aldrich

Anti-P2Y12 Platelet ADP Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-P2RY12, Anti-P2Y12

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MDL编号:
UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

存货情况

not available in Japan

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 7-58 μg/mL using human megakaryocytes

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... P2RY12(64805)
mouse ... P2ry12(70839)
rat ... P2ry12(64803)

一般描述

P2Y12 Platelet ADP Receptor is co-expressed with the P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular calcium upon activation. P2Y12 has also been found in brain, spinal cord, and in vascular

免疫原

synthetic peptide corresponding to the third cytoplasmic loop of human P2Y12 platelet ADP receptor, conjugated to KLH. The immunizing peptide has 83% homology with the rat gene and 89% homology with the mouse gene.

外形

Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bernhard H Rauch et al.
Arteriosclerosis, thrombosis, and vascular biology, 30(12), 2434-2442 (2010-11-13)
The platelet P2Y12 ADP receptor is a well-known target of thienopyridine-type antiplatelet drugs. This study is the first to describe increased transcriptional expression of a functionally active P2Y12 in response to thrombin in human vascular smooth muscle cells (SMC). On

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