P6997
Anti-P2Y12 Platelet ADP Receptor antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-P2RY12, Anti-P2Y12
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
存货情况
not available in Japan
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 7-58 μg/mL using human megakaryocytes
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... P2RY12(64805)
mouse ... P2ry12(70839)
rat ... P2ry12(64803)
一般描述
P2Y12 Platelet ADP Receptor is co-expressed with the P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular calcium upon activation. P2Y12 has also been found in brain, spinal cord, and in vascular
免疫原
synthetic peptide corresponding to the third cytoplasmic loop of human P2Y12 platelet ADP receptor, conjugated to KLH. The immunizing peptide has 83% homology with the rat gene and 89% homology with the mouse gene.
外形
Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Bernhard H Rauch et al.
Arteriosclerosis, thrombosis, and vascular biology, 30(12), 2434-2442 (2010-11-13)
The platelet P2Y12 ADP receptor is a well-known target of thienopyridine-type antiplatelet drugs. This study is the first to describe increased transcriptional expression of a functionally active P2Y12 in response to thrombin in human vascular smooth muscle cells (SMC). On
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