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Merck
CN

P7081

Sigma-Aldrich

1,2-Didecanoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

别名:

PC, (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt, 1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, L-α-Phosphatidylcholine, didecanoyl, Didecanoyllecithin, PC(10:0/10:0)

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关于此项目

经验公式（希尔记法）:
C28H56NO8P
化学文摘社编号:
3436-44-0
分子量:
565.72
Beilstein:
3757665
MDL编号:
MFCD00063538
UNSPSC代码:
51191904
PubChem化学物质编号:
24898817

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方案

≥99% (TLC)

表单

powder

官能团

phospholipid

脂质类型

phosphoglycerides

运输

ambient

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1

InChI key

MLKLDGSYMHFAOC-AREMUKBSSA-N

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储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
120M5222V
120M5222
029K5206
064K5210
055H8377

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C Agerholm et al.
Journal of pharmaceutical sciences, 83(12), 1706-1711 (1994-12-01)
The transepithelial transport of biosynthetic human growth hormone (hGH) formulated with the absorption enhancers didecanoyl-L-alpha-phosphatidylcholine (DDPC) and alpha-cyclodextrin (alpha-CD) was studied after intranasal administration to rabbits. Plasma concentrations of the hormone were determined until 240 min post administration by ELISA
Effect of absorption enhancers on ciliated epithelium: a novel in vivo toxicity screening method using rotifers.
E Adriaens et al.
Pharmaceutical research, 14(4), 541-545 (1997-04-01)
Qunfeng Zhang et al.
Tree physiology, 41(2), 317-330 (2020-10-27)
It is well known that green tea made from fully developed leaves located at the base of young shoots is of lower quality than that made from the still developing leaves located on the top of the shoot. It has
C Vermehren et al.
Drug metabolism and disposition: the biological fate of chemicals, 25(9), 1083-1088 (1997-10-06)
The absorption enhancer, didecanoylphosphatidylcholine (DDPC), improves the nasal absorption of human growth hormone in rabbits. We elucidated the uptake and the metabolism of 1,2-di[1-14C]decanoyl-L-3-phosphatidylcholine and 1,2-didecanoyl-L-3-phosphatidyl[N-methyl-3H]choline in rabbit nasal mucosa in vivo. One minute after nasal application of DDPC, 4.4-7.5%
Vivek S Purohit et al.
The AAPS journal, 8(2), E362-E370 (2006-06-27)
Replacement therapy with exogenous recombinant factor VIII (rFVIII) to control bleeding episodes results in the development of inhibitory antibodies in 15% to 30% of hemophilia A patients. The inhibitory antibodies are mainly directed against specific and universal immunodominant epitopes located
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