P7081
1,2-Didecanoyl-sn-glycero-3-phosphocholine
≥99% (TLC)
别名:
PC, (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt, 1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, L-α-Phosphatidylcholine, didecanoyl, Didecanoyllecithin, PC(10:0/10:0)
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关于此项目
经验公式（希尔记法）:
C28H56NO8P
化学文摘社编号:
分子量:
565.72
PubChem Substance ID:
UNSPSC Code:
51191904
Beilstein/REAXYS Number:
3757665
MDL number:
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O
InChI key
MLKLDGSYMHFAOC-AREMUKBSSA-N
InChI
1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1
assay
≥99% (TLC)
form
powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Qunfeng Zhang et al.
Tree physiology, 41(2), 317-330 (2020-10-27)
It is well known that green tea made from fully developed leaves located at the base of young shoots is of lower quality than that made from the still developing leaves located on the top of the shoot. It has
Effect of absorption enhancers on ciliated epithelium: a novel in vivo toxicity screening method using rotifers.
E Adriaens et al.
Pharmaceutical research, 14(4), 541-545 (1997-04-01)
C Vermehren et al.
Drug metabolism and disposition: the biological fate of chemicals, 25(9), 1083-1088 (1997-10-06)
The absorption enhancer, didecanoylphosphatidylcholine (DDPC), improves the nasal absorption of human growth hormone in rabbits. We elucidated the uptake and the metabolism of 1,2-di[1-14C]decanoyl-L-3-phosphatidylcholine and 1,2-didecanoyl-L-3-phosphatidyl[N-methyl-3H]choline in rabbit nasal mucosa in vivo. One minute after nasal application of DDPC, 4.4-7.5%
C Agerholm et al.
Journal of pharmaceutical sciences, 83(12), 1706-1711 (1994-12-01)
The transepithelial transport of biosynthetic human growth hormone (hGH) formulated with the absorption enhancers didecanoyl-L-alpha-phosphatidylcholine (DDPC) and alpha-cyclodextrin (alpha-CD) was studied after intranasal administration to rabbits. Plasma concentrations of the hormone were determined until 240 min post administration by ELISA
Cécile Loudet et al.
Biochimica et biophysica acta, 1724(3), 315-323 (2005-06-18)
Mixtures of dicaproyl- (DC), dimyristoyl- (DM) and 1-tetradecanoyl-2-biphenylbutanoyl-(TBB) phosphatidylcholine (PC) in water produce bicelle membranes that are oriented by magnetic fields. DMPC/DCPC systems orient such that their membrane plane is parallel to the magnetic field, whereas for TBBPC/DCPC, the plane
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