type
Type II
form
lyophilized powder
specific activity
4-8 units/mg protein
packaging
vial of ~25 units
foreign activity
5′-nucleotidase <0.003 units/mg protein, alkaline phosphatase <0.002 units/mg protein, phosphodiesterase 0.2 - 0.4 units/mg protein
storage temp.
−20°C
Physical form
Lyophilized powder containing approx. 35% Tris buffer salts.
Other Notes
One unit will hydrolyze 1.0 μmole of β-NAD to NMN and AMP per min at pH 7.4 at 37 °C in the presence of Mg ions.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Soheil Naderi et al.
Human immunology, 69(12), 833-836 (2008-10-07)
Defects in Fas receptor signaling lead to compromised maintenance of lymphocyte homeostasis and peripheral immune tolerance, leading in turn to autoimmune disorders. Therefore, agents that can enhance Fas-mediated apoptosis may be therapeutically useful in management of such disorders. In this
Violeta López-Canut et al.
Journal of the American Chemical Society, 132(20), 6955-6963 (2010-05-01)
We here present a theoretical study of the alkaline hydrolysis of methyl p-nitrophenyl phosphate (MpNPP(-)) in aqueous solution and in the active site of nucleotide pyrophosphatase/phosphodiesterase (NPP). The analysis of our simulations, carried out by means of hybrid quantum mechanics/molecular
Khalid M Khan et al.
Bioorganic & medicinal chemistry, 17(22), 7816-7822 (2009-10-14)
A series of 1,3,4-oxadiazole-2 (3H)-thiones and 1,3,4-thiadiazole-2 (3H)-thiones were synthesized and evaluated for their inhibitory activities against the two nucleotide pyrophosphatase phosphodiesterase 1 enzymes. Dixon, as well as Lineweaver-Burk plots, and their secondary replots have indicated that the inhibition was
Shiro Ikegawa
Clinical calcium, 21(2), 294-300 (2011-02-04)
ttw (tiptoe walking), a known model mouse of OPLL (ossification of the posterior longitudinal ligament of the spine) is reviewed. ttw is a natural mutant which shows generalized ectopic calcification followed by ossification in the Achiles tendon, ear and spinal
Jamshed Iqbal et al.
Electrophoresis, 29(17), 3685-3693 (2008-09-23)
A new highly sensitive capillary electrophoresis (CE) method applying dynamic coating and on-line stacking for the monitoring of nucleotide pyrophosphatases/phosphodiesterases (NPPs) and the screening of inhibitors was developed. NPP1 and NPP3 are membrane glycoproteins that catalyze the hydrolysis nucleotides, e.g.
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