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Merck
CN

P8087

Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse

clone 15F11, ascites fluid, buffered aqueous solution

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
15F11, monoclonal
Application:
ARR, ICC, IF, IHC (f), IP, WB
Citations:
16
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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

15F11, monoclonal

form

buffered aqueous solution

mol wt

antigen 85 kDa

contains

15 mM sodium azide

species reactivity

bovine, canine, human

technique(s)

immunocytochemistry: suitable using cultured cells, immunohistochemistry (frozen sections): suitable, immunoprecipitation (IP): suitable, indirect immunofluorescence: 1:1,000 using cultured MDBK cells, microarray: suitable, western blot: 1:2,000 using cultured MDBK cells

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... JUP(3728)

General description

Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .

Immunogen

recombinant chicken plakoglobin.

Application

Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).

Biochem/physiol Actions

The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
动物来源生物产品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容

Instructions






全球贸易项目编号

货号GTIN
P8087-.2ML04061837873546
P8087-100UL04061837873553