biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 65 kDa
species reactivity
bovine, human, rat, mouse
concentration
~1 mg/mL
technique(s)
immunocytochemistry: 10-15 μg/mL, microarray: suitable, western blot: 5-10 μg/mL using total rat brain homogenate
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PPP2CA(5515)
mouse ... Ppp2ca(19052)
rat ... Ppp2ca(24672)
General description
Protein Phosphatase 2A (PP2A) is a protein that belongs to serine/threonine-specific protein phosphatases family. It has a pivotal role in several cellular processes like DNA replication, transcription, RNA splicing, translation, cellular metabolism, cell-cycle progression, morphogenesis, development and transformation. Anti-serine/threonine protein phosphatase 2 A/A antibody can be used for detecting protein phosphatase 2A/A isoforms by using immunoprecipitation. It can also be used in immunocytochemistry. Rabbit anti-serine/threonine protein phosphatase 2 A/A antibody reacts specifically with protein phosphatase 2A/A isoforms (65kD) from mouse, bovine, rat and human.
Immunogen
synthetic peptide corresponding to the N-terminus (amino acids 7-19) of the protein phosphatase 2A structural subunit.
Application
Anti-serine/threonine protein phosphatase 2 A/A antibody can be used in western blotting using total rat brain homogenate. It can also be used in microarray.
Physical form
Solution in phosphate buffered saline containing 0.08% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
法规信息
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此项目有
R E Mayer-Jaekel et al.
Trends in cell biology, 4(8), 287-291 (1994-08-01)
Protein phosphorylation is probably the major regulatory mechanism employed by eukaryotic cells. Much work has been devoted to the role of protein kinases and their modulation by hormones, growth factors and neurotransmitters. It is now appreciated that protein phosphatases are
Serine/threonine protein phosphatases.
S Wera et al.
The Biochemical journal, 311 ( Pt 1), 17-29 (1995-10-01)
W Rozek et al.
Polish journal of veterinary sciences, 16(4), 663-669 (2013-01-01)
Changes in the level of cellular proteins in cells inoculated with equine influenza virus H7N7 and H3N8 were studied with microarray technique. H3N8 induced pro-apoptotic proteins while H7N7 induced both pro- as well as anti-apoptotic factors. The higher level of
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P8109-.1ML | 04061838164742 |
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