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Merck
CN

P8109

Anti-Serine/Threonine Protein Phosphatase 2 A/A antibody produced in rabbit

~1 mg/mL, IgG fraction of antiserum, buffered aqueous solution

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.44
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ARR, ICC, WB
Citations:
3
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 65 kDa

species reactivity

bovine, human, rat, mouse

concentration

~1 mg/mL

technique(s)

immunocytochemistry: 10-15 μg/mL, microarray: suitable, western blot: 5-10 μg/mL using total rat brain homogenate

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PPP2CA(5515)
mouse ... Ppp2ca(19052)
rat ... Ppp2ca(24672)

General description

Protein Phosphatase 2A (PP2A) is a protein that belongs to serine/threonine-specific protein phosphatases family. It has a pivotal role in several cellular processes like DNA replication, transcription, RNA splicing, translation, cellular metabolism, cell-cycle progression, morphogenesis, development and transformation. Anti-serine/threonine protein phosphatase 2 A/A antibody can be used for detecting protein phosphatase 2A/A isoforms by using immunoprecipitation. It can also be used in immunocytochemistry. Rabbit anti-serine/threonine protein phosphatase 2 A/A antibody reacts specifically with protein phosphatase 2A/A isoforms (65kD) from mouse, bovine, rat and human.

Immunogen

synthetic peptide corresponding to the N-terminus (amino acids 7-19) of the protein phosphatase 2A structural subunit.

Application

Anti-serine/threonine protein phosphatase 2 A/A antibody can be used in western blotting using total rat brain homogenate. It can also be used in microarray.

Physical form

Solution in phosphate buffered saline containing 0.08% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R E Mayer-Jaekel et al.
Trends in cell biology, 4(8), 287-291 (1994-08-01)
Protein phosphorylation is probably the major regulatory mechanism employed by eukaryotic cells. Much work has been devoted to the role of protein kinases and their modulation by hormones, growth factors and neurotransmitters. It is now appreciated that protein phosphatases are
Serine/threonine protein phosphatases.
S Wera et al.
The Biochemical journal, 311 ( Pt 1), 17-29 (1995-10-01)
W Rozek et al.
Polish journal of veterinary sciences, 16(4), 663-669 (2013-01-01)
Changes in the level of cellular proteins in cells inoculated with equine influenza virus H7N7 and H3N8 were studied with microarray technique. H3N8 induced pro-apoptotic proteins while H7N7 induced both pro- as well as anti-apoptotic factors. The higher level of

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全球贸易项目编号

货号GTIN
P8109-.1ML04061838164742

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