assay
≥95%
form
powder
color
yellow
storage temp.
−20°C
SMILES string
CC1C(OC(=O)\C=C(C)\C=C\C=C(C)\C=C\C2=C(C)CCCC2(C)C)C3(OC(C)=O)C(C4C=C(CO)CC5(O)C(C=C(C)C5=O)C14O)C3(C)C
InChI
1S/C42H56O8/c1-24(16-17-31-26(3)15-12-18-38(31,7)8)13-11-14-25(2)19-34(45)49-37-28(5)41(48)32(35-39(9,10)42(35,37)50-29(6)44)21-30(23-43)22-40(47)33(41)20-27(4)36(40)46/h11,13-14,16-17,19-21,28,32-33,35,37,43,47-48H,12,15,18,22-23H2,1-10H3/b14-11+,17-16+,24-13+,25-19+/t28-,32+,33-,35-,37-,40-,41-,42-/m1/s1
InChI key
GTNCUWBKHZZECN-IXTPSRJDSA-N
Biochem/physiol Actions
Skin tumor promoter.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Kumiko Tanabe et al.
Journal of neurochemistry, 106(2), 519-528 (2008-04-04)
Dexmedetomidine (Dexmd), a potent and highly specific alpha(2) adrenoreceptor agonist, is an efficient therapeutic agent for sedation. Dexmd has been recently reported to have a neuroprotective effect. Heat shock protein (HSP) 27, a low-molecular weight HSP has been shown to
Spike timing-dependent long-term potentiation in ventral tegmental area dopamine cells requires PKC.
Percy Luu et al.
Journal of neurophysiology, 100(1), 533-538 (2008-05-03)
Long-term potentiation (LTP) of excitatory synapses on ventral tegmental area (VTA) dopamine (DA) cells is thought to play an important role in mediating some of the behavioral effects of drugs of abuse yet little is known about its underlying mechanisms.
S Rajagopal et al.
Neuroscience, 159(2), 618-628 (2009-01-27)
Ca(v)2.2 high voltage-gated calcium channels are regulated by phorbol-12-myristae, 13-acetate (PMA) via Ser/Thr protein kinase C (PKC) phosphorylation sites in the I-II linker and C-terminus of the alpha(1) 2.2 subunit. Here we show that PMA enhancement of Ca(v)2.2 currents expressed