Monoclonal Anti-HLA-DR−PE antibody produced in mouse

HLA-DR is located on chromosome 6. It is composed of a heavy and light chain, which are two non-covalently associated subunits of molecular weight 33-36 kDa and 24-30 kDa, respectively. These class II antigens are expressed primarily on B cells, and on monocytes and activated T cells, and function in cell-cell recognition in regulation of the immune response.

The previously assigned protein identifier P13761 has been merged into P01911. Full details can be found on the UniProt database.

GM-1500 human tumor cell line

Recognizes HLA-DR, a product of the human major histocompatibility complex. The antibody is specific for a non-polymorphic HLA-DR determinant.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Prepared by conjugation to R-phycoerythrin (PE). This orange-red dye is efficiently excited at 488 nm and emits at 578 nm.

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