P9868
Anti-Protein Phosphatase 5 (PP5) antibody produced in rabbit
buffered aqueous solution, fractionated antiserum, pkg of ~100 μg, 1 mg/mL
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
fractionated antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 58 kDa
种属反应性
human
包装
pkg of ~100 μg
浓度
1 mg/mL
技术
western blot: 5-10 μg/mL using A549 or MCF7 cell lysates
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... PPP5C(5536)
一般描述
Ser/Thr protein phosphatase type 5 (PP5) is a 58kD protein present in human and is localized in nucleus which plays an essential role in mitosis and in the regulation of RNA biogenesis. It also has a pivotal role in cell proliferation and facilitates neoplastic transformation. Rabbit Anti-Protein Phosphatase 5 (PP5) antibody can identify human PP5 and reacts specifically with protein serine threonine phosphatase 5 (58 kD).
免疫原
synthetic peptide derived from the human phosphatase 5 protein.
应用
Anti-Protein Phosphatase 5 (PP5) antibody can be used in western blotting using A549 or MCF7 cell lysates.
外形
Solution in phosphate buffered saline containing 0.08% sodium azide. The amount of the reagent is sufficient for 10 blots.
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储存分类代码
10 - Combustible liquids
法规信息
新产品
此项目有
M Chinkers
Trends in endocrinology and metabolism: TEM, 12(1), 28-32 (2001-01-04)
Protein phosphatase 5 (PP5) possesses unique biochemical properties, which include its tetratricopeptide repeat (TPR) targeting/regulatory domain and its ability to be activated by lipids. PP5 has been studied as a paradigm for TPR protein structure and function. Roles for PP5
Z Zuo et al.
Biochemistry, 38(28), 8849-8857 (1999-07-22)
Ligand-induced glucocorticoid receptor (GR) activation has recently been linked to the inhibition of cell proliferation via the transcriptional induction of p21(WAF1/Cip1), which functions as a universal inhibitor of cyclin-dependent protein kinases. Herein, we identify a Ser/Thr protein phosphatase (PP5) that
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