Goat anti-Rad17 Antibody, Affinity Purified

The epitope recognized by PLA0051 maps to a region between residues 325 and 375 of human Rad17 using the numbering given in entry NP_002864.1 (GeneID 5884).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Rad17 is a cell cycle checkpoint protein that associates with the RFC complex to recruit the 9-1-1 complex (Rad9, Hus1, Rad1) to sites of DNA damage. At DNA lesions, Rad17 and RFC aid in the activation of Chk2 by ATM and ATRIP to trigger the checkpoint signaling cascade for G2 arrest.

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