生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
种属反应性
primate, rhesus monkey, human, dog, chimpanzee, gorilla, pig, rabbit, horse
浓度
1 mg/mL
技术
western blot: 1:500- 1:5,000
登记号
NP_001265.1
运输
wet ice
储存温度
2-8°C
基因信息
human ... CHEK1(1111)
免疫原
Immunogen for PLA0056 was a phosphorylated synthetic peptide, which represented a portion of human Checkpoint Kinase 1 (GeneID 1111) around serine 317 according to the numbering given in entry NP_001265.1.
外形
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
其他说明
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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B P Kaistha et al.
British journal of cancer, 111(9), 1780-1787 (2014-08-20)
Pancreatic ductal adenocarcinoma (PDAC) is among the most aggressive human malignancies with an overall 5-year survival rate of <5%. Despite significant advances in treatment of the disease during the past decade, the median survival rate (∼6 months) has hardly improved
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