Rabbit anti-RFC3 Antibody, Affinity Purified

The epitope recognized by PLA0059 maps to a region between residues 30 and 80 of human replication factor C (Activator 1) 3, 38kDa using the numbering given in SwissProt entry P40938 (GeneID 5983).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

The Replication factor C (RFC) heteropentamer includes RFC1, RFC2, RFC3, RFC4, and RFC5. The RFC heteropentamer is part of the multiprotein DNA replicase that functions to replicate DNA prior to cell division and repair DNA damage. RFC is the clamp loader ATPase associated with the DNA replicase. As the clamp loader, RFC uses ATP to recruit, open, and close the PCNA ring to link it to DNA for replication and repair. RFC3 is the 38 kDa subunit of RFC that is essential for the interaction between RFC1 and the core formed by RFC2, RFC4, and RFC5.

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