biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
mouse, human
technique(s)
immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:1,000- 1:5,000
accession no.
NP_055387.1
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
rabbit ... LATS2(26524)
Immunogen
The epitope recognized by PLA0110 maps to a region between residues 1 and 50 of human Large Tumor Suppressor 2 using the numbering given in entry NP_055387.1 (GeneID 26524).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
LATS2 (Large Tumor Suppressor homolog 2) has been identified as a tumor suppressor protein and is a member of the Dbf2-related (NDR) family of protein kinases that are key components of the mitotic exit network. LATS2 appears to negatively regulate G2/M transitioning by down-regulating CDC2 kinase activity. LATS2 has also been identified as a negative regulator of the androgen receptor (AR) and may play a role in AR-mediated transcription and the development of prostate cancer.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Masahiro Tsujiura et al.
PloS one, 9(6), e100974-e100974 (2014-06-28)
Yes-associated protein (YAP) is a transcriptional co-activator and regulates cell proliferation and apoptosis. We investigated the clinical and biological significance of YAP in endometrial cancer (EMCA). YAP expression in 150 primary tumor tissues from patients with EMCA was evaluated by
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