PLA0122
Rabbit anti-Chk2 Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
别名:
CDS1, CHK2, CHK2 (checkpoint; S.pombe) homolog, CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Checkpoint kinase 2, HuCds1, LFS2, PP1425, RAD53, bA444G7, cds1 homolog, checkpoint-like protein CHK2, hCds1
biological source
rabbit
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
human
technique(s)
immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:2,000-1:10,000
accession no.
NP_009125.1
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Gene Information
rabbit ... Chk2(11200)
Immunogen
The epitope recognized by PLA0122 maps to a region between residues 1 and 50 of human Checkpoint Kinase 2 using the numbering given in entry NP_009125.1 (GeneID 11200).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are Rad53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, BRCA1, Cdc25A and Cdc25C to cause cell cycle arrest.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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