Rabbit anti-PHF8 Antibody, Affinity Purified

The epitope recognized by PLA0211 maps to a region between residue 650 and 700 of human PHD finger protein 8 using the numbering given in entry CAI41576.1 (GeneID 23133).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate.

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