Rabbit anti-CDC6 Antibody, Affinity Purified

The epitope recognized by PLA0257 maps to a region between residue 510 and 560 of human cell division cycle 6 using the numbering given in entry NP_001245.1 (GeneID 990).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Cell division cycle protein 6 homolog (CDC6) is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during the cell cycle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins [taken from NCBI Entrez Gene (GeneID: 990)].

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.