PZ0393
Oxamniquine
≥98% (HPLC)
别名:
(2-((isopropylamino)methyl)-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl)methanol, 1,2,3,4-Tetrahydro-2-[[(1-methylethyl)amino]methyl]-7-nitro-6-quinolinemethanol
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关于此项目
经验公式（希尔记法）:
C14H21N3O3
化学文摘社编号:
分子量:
279.33
UNSPSC Code:
41121800
NACRES:
NA.77
MDL number:
SMILES string
[N+](=O)([O-])c1cc2c(cc1CO)CCC(N2)CNC(C)C
InChI
1S/C14H21N3O3/c1-9(2)15-7-12-4-3-10-5-11(8-18)14(17(19)20)6-13(10)16-12/h5-6,9,12,15-16,18H,3-4,7-8H2,1-2H3
InChI key
XCGYUJZMCCFSRP-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
faint yellow to dark brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
room temp
Biochem/physiol Actions
Oxamniquine is an anthelmintic agent with schistosomicidal activity against Schistosoma mansoni.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Gordana Panic et al.
Antimicrobial agents and chemotherapy, 61(12) (2017-10-04)
To date, there is only one drug in use, praziquantel, to treat more than 250 million people afflicted with schistosomiasis, a debilitating parasitic disease. The aryl hydantoin Ro 13-3978 is a promising drug candidate with in vivo activity superior to
Lidiany da Paixão Siqueira et al.
Acta tropica, 176, 179-187 (2017-08-15)
Neglected tropical diseases (NTDs) affect millions of people in different geographic regions, especially the poorest and most vulnerable. Currently NTDs are prevalent in 149 countries, seventeen of these neglected tropical parasitic diseases are classified as endemic. One of the most
Anastasia Rugel et al.
ACS medicinal chemistry letters, 9(10), 967-973 (2018-10-23)
Schistosomiasis is a major human parasitic disease afflicting more than 250 million people, historically treated with chemotherapies praziquantel or oxamniquine. Since oxamniquine is species-specific, killing Schistosoma mansoni but not other schistosome species (S. haematobium or S. japonicum) and evidence for
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