Q108
R(−)-Quinuclidinyl benzilate methiodide
crystalline
别名:
R(−)-QNB methiodide, R(−)-Quinuclidinyl-α-hydroxydiphenylacetate methiodide
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关于此项目
经验公式（希尔记法）:
C22H26INO3
分子量:
479.35
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C22H26NO3.HI/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,17,20,25H,12-16H2,1H3;1H/q+1;/p-1/t17?,20-,23?;/m0./s1
SMILES string
[I-].C[N+]12CCC(CC1)[C@H](C2)OC(=O)C(O)(c3ccccc3)c4ccccc4
InChI key
YCVUWYMRBRAYRO-TULJGGFASA-M
form
crystalline
color
white
solubility
ethanol: soluble
storage temp.
2-8°C
Biochem/physiol Actions
Nonselective muscarinic acetylcholine receptor antagonist.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
M Waelbroeck et al.
Molecular pharmacology, 40(3), 413-420 (1991-09-01)
We analyzed the competition kinetics of quinuclidinyl benzilate (QNB) and QNB methiodide enantiomers on human NB-OK1 neuroblastoma (M1), rat cardiac (M2), and rat pancreas (M3) muscarinic binding sites. The association rate constants of the four drugs depended on the receptor
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