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Merck
CN

R3143

Ribonucleic acid, transfer, phenylalanine specific from Escherichia coli MRE 600

lyophilized powder

别名:

E. coli Phe tRNA

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关于此项目

UNSPSC Code:
12352200
MDL number:
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grade

Molecular Biology

form

lyophilized powder

storage temp.

−20°C

General description

Transfer RNA is isolated from E. coli MRE 600. This transfer RNA is specific for transfer of the amino acid phenylalanine.

Application

Suitable for use:
  • As a tRNA standard
  • As a substrate uin tRNA synthatase assays
  • As a substrate in other reactions involving tRNAs

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Jiqiang Ling et al.
RNA (New York, N.Y.), 13(11), 1881-1886 (2007-09-07)
Translational quality control is monitored at several steps, including substrate selection by aminoacyl-tRNA synthetases (aaRSs), and discrimination of aminoacyl-tRNAs by elongation factor Tu (EF-Tu) and the ribosome. Phenylalanyl-tRNA synthetase (PheRS) misactivates Tyr but is able to correct the mistake using
V Serebrov et al.
Nucleic acids research, 26(11), 2723-2728 (1998-05-21)
Mature tRNAPhe from Escherichia coli and the transcript of its gene lacking modified nucleotides were compared by a variety of physical techniques. Melting experiments revealed that at a low Mg2+level the transcript was partially denatured, while the mature tRNA possessed
Noa Aharon-Hefetz et al.
eLife, 9 (2020-12-29)
Different subsets of the tRNA pool in human cells are expressed in different cellular conditions. The 'proliferation-tRNAs' are induced upon normal and cancerous cell division, while the 'differentiation-tRNAs' are active in non-dividing, differentiated cells. Here we examine the essentiality of

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