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Merck
CN

R5380

N-Acetyl-Renin Substrate Tetradecapeptide porcine

≥97% (HPLC), suitable for MALDI-MS

别名:

Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser

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关于此项目

经验公式（希尔记法）:
C87H125N21O21
化学文摘社编号:
66641-26-7
分子量:
1801.05
PubChem Substance ID:
24899380
UNSPSC Code:
12352200
MDL number:
MFCD00133568

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产品名称

N-Acetyl-Renin Substrate Tetradecapeptide porcine, ≥97% (HPLC)

InChI

1S/C87H125N21O21/c1-12-49(10)72(107-80(122)63(36-53-24-28-57(112)29-25-53)102-82(124)70(47(6)7)105-73(115)58(20-16-30-92-87(88)89)96-78(120)65(39-69(113)114)95-50(11)110)84(126)103-66(38-55-41-91-44-94-55)85(127)108-31-17-21-68(108)81(123)100-61(34-51-18-14-13-15-19-51)75(117)99-64(37-54-40-90-43-93-54)77(119)97-59(32-45(2)3)74(116)98-60(33-46(4)5)79(121)106-71(48(8)9)83(125)101-62(35-52-22-26-56(111)27-23-52)76(118)104-67(42-109)86(128)129/h13-15,18-19,22-29,40-41,43-49,58-68,70-72,109,111-112H,12,16-17,20-21,30-39,42H2,1-11H3,(H,90,93)(H,91,94)(H,95,110)(H,96,120)(H,97,119)(H,98,116)(H,99,117)(H,100,123)(H,101,125)(H,102,124)(H,103,126)(H,104,118)(H,105,115)(H,106,121)(H,107,122)(H,113,114)(H,128,129)(H4,88,89,92)

SMILES string

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(O)=O)NC(C)=O)C(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)N3CCCC3C(=O)NC(Cc4ccccc4)C(=O)NC(Cc5cnc[nH]5)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc6ccc(O)cc6)C(=O)NC(CO)C(O)=O

InChI key

IUJUQXJOVSWPHY-UHFFFAOYSA-N

assay

≥97% (HPLC)

form

powder

technique(s)

MALDI-MS: suitable

color

white

storage temp.

−20°C

Quality Level

200

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLBR2322V
SLBJ7810V
091M8716V
041M8745V
041M8745

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T C Cheng et al.
Protein science : a publication of the Protein Society, 8(11), 2474-2486 (1999-12-14)
A novel metallocarboxypeptidase (PfuCP) has been purified to homogeneity from the hyperthermophilic archaeon, Pyrococcus furiosus, with its intended use in C-terminal ladder sequencing of proteins and peptides at elevated temperatures. PfuCP was purified in its inactive state by the addition
Jadwiga Dudkiewicz-Wilczyńska et al.
Acta poloniae pharmaceutica, 61(3), 171-174 (2004-10-16)
A high-performance liquid chromatographic assay has been developed to the separation of angiotensin I, tetradecapeptide and the tetrapeptide Leu-Val-Tyr-Ser. This purpose is achieved in a single step, using HPLC technique in the reversed phase system. The method is based on
C F Santos et al.
Journal of periodontology, 80(1), 130-139 (2009-02-21)
The systemic renin-angiotensin system (RAS) promotes the plasmatic production of angiotensin (Ang) II, which acts through interaction with specific receptors. There is growing evidence that local systems in various tissues and organs are capable of generating angiotensins independently of circulating
Khalid M Elased et al.
Hypertension (Dallas, Tex. : 1979), 46(4), 953-959 (2005-08-17)
This article demonstrates the applicability of quantitative proteomics to assays of proteolytic enzyme activity. A novel assay was developed for measurement of renin and angiotensin-converting enzyme (ACE) activity in plasma. The method was validated in animal models associated with alterations

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