R9010
Monoclonal Anti-Rat Kappa Light Chains (1a + 1b) antibody produced in mouse
clone RT-39, ascites fluid
别名:
Monoclonal Anti-Rat Kappa Light Chains (1a + 1b)
生物来源
mouse
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
secondary antibodies
克隆
RT-39, monoclonal
分子量
antigen 25 kDa
包含
15 mM sodium azide
技术
capture ELISA: suitable
dot blot: suitable
immunocytochemistry: suitable
indirect ELISA: 1:2,000
western blot: suitable using denatured and reduced normal serum or myeloma protein
同位素/亚型
IgG1
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
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一般描述
Monoclonal anti-Rat Light Chain (1a+1b) (mouse IgG1 isotype) is derived from the RT-39 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified rat IgG. An immunoglobulin (Ig) has two heavy chain and two light chain connected by disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Rat has five immunoglobulin classes- IgM, IgG, IgA, IgD and IgGE. IgG has four subclasses- IgG1, IgG2a, IgG2b and IgG2c. Rat immunoglobulins have either κ or λ light chains. Greater than 90% of normal rat immunoglobulins and myelomas contain light chains.
免疫原
Purified rat IgG
应用
Monoclonal Anti-Rat κ Light Chains (1a + 1b) antibody has been used in capture enzyme linked immunosorbent assay (ELISA), immunoblotting, dot blot and immunocytochemistry.
Monoclonal Anti-Rat Kappa Light Chains (1a + 1b) antibody produced in mouse has been used in:
- enzyme-linked immunosorbent assay (ELISA)
- immunoblotting
- dot blot
- immunocytochemistry
生化/生理作用
Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III reactions. It helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
The antibody reacts with an epitope on the rat κ light chain, which is shared by both the 1a and 1b allotypes in various rat immunoglobulin classes and subclasses. No cross-reactivity is observed with rat λ light chains or with IgG from human, mouse, bovine, rabbit, goat, sheep, horse, dog, chicken, pig or cat. The product shows weak cross-reaction with guinea pig IgG.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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