RAB0209
胃抑制肽EIA试剂盒
for serum, plasma, culture supernatant and cell lysates
别名:
GIP, Gastric inhibitory polypeptide , Glucose-dependent insulinotropic polypeptide, Incretin hormone
species reactivity
mouse, rat, human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, enzyme immunoassay: suitable
input
sample type serum
sample type culture supernatant(s)
sample type plasma
sample type cell lysate
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 0.125 pg/mL
standard curve range: 0.1–1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GIP(2695)
General description
Glucose-dependent insulinotropic polypeptide (GIP) is a 42-amino acid gastrointestinal regulatory peptide, expressed in K cells of the small intestine and in cells of the submandibular salivary gland.
Immunogen
Gastric Inhibitory Peptide (GIP), synthetic peptide
Application
Gastric inhibitory peptide has been used in enzyme immunoassay.
Biochem/physiol Actions
In the presence of glucose, glucose-dependent insulinotropic polypeptide (GIP) induces insulin secretion. It acts as an antagonist of the human GIP receptor. Aberrations in GIP are associated with visceral fat accumulation.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
低风险生物材料
常规特殊物品
此项目有
The gluco-and liporegulatory and vasodilatory effects of glucose-dependent insulinotropic polypeptide (GIP) are abolished by an antagonist of the human GIP receptor.
Asmar M, et al.
Diabetes, 66(9), 2363-2371 (2017)
Incretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis.
Srivastava S, et al.
Biomedicine and Pharmacotherapy, 97, 330-338 (2018)
Tao Hao et al.
International journal of molecular medicine, 39(4), 1029-1036 (2017-03-16)
Long-term exposure to a high-fat diet (HFD) causes glucotoxicity and lipotoxicity in islet β cells and leads to the development of metabolic dysfunctions. Reductions in pancreatic and duodenal homeobox-1 (PDX-1) expression have been shown to induce type 2 diabetes mellitus by causing impairments to
Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line.
Boylan MO, et al.
The Journal of Biological Chemistry, 272(28), 17438-17443 (1997)
Common variants of GIP are associated with visceral fat accumulation in Japanese adults.
Nakayama K, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 307(11), G1108-G1114 (2014)
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持