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Merck
CN

RES1520C-A7

SAFC

胱氨酸

别名:

L -胱氨酸, (R,R)-3,3′-亚二硫基二(2-丙氨酸)

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关于此项目

线性分子式:
[-SCH2CH(NH2)CO2H]2
化学文摘社编号:
分子量:
240.30
Beilstein:
1728094
EC 号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.21
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生物来源

plant

方案

98.5-101.0% dry basis

表单

powder

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

mp

>240 °C (dec.) (lit.)

适用性

suitable for manufacturing use

异质活性

Cytotoxicity; tested

SMILES字符串

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

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应用

L-胱氨酸是一种含硫的非必需氨基酸。它用作治疗性重组蛋白和单克隆抗体的商业生物制造的细胞培养基成分和原料。

包装

该产品有以下包装尺寸:
RES1520C-A701X:100gm 包装
RES1520C-A702X:1kg 包装
RES1520C-A704X:10kg 包装
RES1520C-A705X:25kg 包装

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anne C Conibear et al.
The Journal of biological chemistry, 288(15), 10830-10840 (2013-02-23)
θ-Defensins are ribosomally synthesized cyclic peptides found in the leukocytes of some primate species and have promising applications as antimicrobial agents and scaffolds for peptide drugs. The cyclic cystine ladder motif, comprising a cyclic peptide backbone and three parallel disulfide
Philip J Hogg
Nature reviews. Cancer, 13(6), 425-431 (2013-05-11)
Protein action in nature is generally controlled by the amount of protein produced and by chemical modification of the protein, and both are often perturbed in cancer. The amino acid side chains and the peptide and disulphide bonds that bind
T Terada et al.
Archives of biochemistry and biophysics, 300(1), 495-500 (1993-01-01)
Low concentrations of cystamine and cystine inactivated human placenta glutathione S-transferase (GST-pi) in cytosolic fraction very effectively, as did the purified enzyme, through the thiol/disulfide exchange reaction. Mixed disulfide formation of GST-pi in cytosol was prevented by thioltransferase existing in
Serge-George Rosolen et al.
Advances in experimental medicine and biology, 775, 145-154 (2013-02-09)
In the 70s, the amino acid taurine was found essential for photoreceptor survival. Recently, we found that taurine depletion can also trigger retinal ganglion cell degeneration both in vitro and in vivo. Therefore, evaluation of taurine levels could be a
Ojore Benedict Valentine Oka et al.
Molecular cell, 50(6), 793-804 (2013-06-19)
ERdj5 is a member of the protein disulfide isomerase family of proteins localized to the endoplasmic reticulum (ER) of mammalian cells. To date, only a limited number of substrates for ERdj5 are known. Here we identify a number of endogenous

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