S0695
Anti-Somatostatin Receptor Type 2 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-SSTR2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
availability
not available in Japan
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 24 μg/mL using human pancreas, Islets of Langerhans (Optimal dilution should be determined by the researcher.)
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
human ... SSTR2(6752)
mouse ... Sstr2(20606)
rat ... Sstr2(54305)
General description
Somatostatin receptor 2 (SSTR2) is encoded by the gene mapped to human chromosome 17q25.1. It is mainly localized on choroid plexus and arachnoid granulations. SSTR2 is transcribed into two isoforms, SSTR2A and SSTR2B through alternative splicing.
Immunogen
synthetic peptide corresponding to the second extracellular loop of human somatostatin receptor type 2, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.
Biochem/physiol Actions
Somatostatin receptor 2 (SSTR2) mediates human anterior pituitary hormone suppression by interacting with its peptide ligand somatostatin. It also plays a major role in maintenance of brain fluid homeostasis. The encoded protein has an ability to hinder the cell proliferation of solid tumors. Experimental studies states that SSTR2 methylation is presumed to be involved in the metastasis and invasion of laryngeal cancer.
Physical form
Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Genetic analysis of inherited hydrocephalus in a rat model
Jones HC, et al.
Experimental Neurology, 190, 79-90 (2004)
SSTR2 promoter hypermethylation is associated with the risk and progression of laryngeal squamous cell carcinoma in males
Shen Z, et al.
Diagnostic Pathology (2016)
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持