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Merck
CN

S1072

Anti-Sodium Channel ASIC4 兔抗

affinity isolated antibody, lyophilized powder

别名:

Anti-ACCN4, Anti-H+-gated cation channel, Anti-SPASIC

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

western blot: 1:200-1:500 using rat brain lysate, ND7/23 cell line lysate, and rat dorsal root ganglion (DRG) lysate

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Accn4(63882)

General description

Sodium Channel ASIC4 is a member of the ASIC family that also includes ASIC1, ASIC2 and ASIC3. The ASIC family is part of a large channel superfamily known as degenerin/epithelial sodium channels (DEG/ENaC). The functional ASIC channel is composed of 4 subunits, which can form either a homo or heterotetramer. ASIC4 protein does not appear to function as a proton-gated channel when expressed alone in heterologous systems and therefore a modulatory role for this subunit has been proposed. ASIC4 protein is expressed in brain, pituitary gland, spinal cord and inner ear.

Immunogen

peptide CKIKFAEEDAKPKEKEAGDE corresponding to residues 7-26 of N-terminal rat Accn4.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

Preparation Note

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

13 - Non Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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相关内容

Instructions


Amra Saric et al.
Molecular biology of the cell, 27(2), 321-333 (2015-11-20)
Macrophages and dendritic cells exposed to lipopolysaccharide (LPS) convert their lysosomes from small, punctate organelles into a network of tubules. Tubular lysosomes have been implicated in phagosome maturation, retention of fluid phase, and antigen presentation. There is a growing appreciation
Blandine Monel et al.
The EMBO journal, 36(12), 1653-1668 (2017-05-06)
The cytopathic effects of Zika virus (ZIKV) are poorly characterized. Innate immunity controls ZIKV infection and disease in most infected patients through mechanisms that remain to be understood. Here, we studied the morphological cellular changes induced by ZIKV and addressed
Priya Crosby et al.
Cell, 177(4), 896-909 (2019-04-30)
In mammals, endogenous circadian clocks sense and respond to daily feeding and lighting cues, adjusting internal ∼24 h rhythms to resonate with, and anticipate, external cycles of day and night. The mechanism underlying circadian entrainment to feeding time is critical for



全球贸易项目编号

货号GTIN
S1072-50UL04061838032980
S1072-200UL04061835686681