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Merck
CN

S1634

L-Saccharopine

别名:

ε-N-(L-glutar-2-yl)-L-lysine, N6-(L-1,3-dicarboxylpropyl)-L-lysine

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关于此项目

经验公式(希尔记法):
C11H20N2O6
化学文摘社编号:
分子量:
276.29
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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assay

≥98%

form

powder

color

white

storage temp.

−20°C

SMILES string

N[C@@H](CCCCN[C@@H](CCC(O)=O)C(O)=O)C(O)=O

InChI

1S/C11H20N2O6/c12-7(10(16)17)3-1-2-6-13-8(11(18)19)4-5-9(14)15/h7-8,13H,1-6,12H2,(H,14,15)(H,16,17)(H,18,19)/t7-,8-/m0/s1

InChI key

ZDGJAHTZVHVLOT-YUMQZZPRSA-N

Preparation Note

Prepared enzymatically

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

存储类别

11 - Combustible Solids

法规信息

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历史批次信息供参考:

分析证书(COA)

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J Dancis et al.
American journal of human genetics, 31(3), 290-299 (1979-05-01)
Enzyme assays of skin fibroblasts from five children with familial hyperlysinemia from unrelated families are added to the previous report of three children from two unrelated families. In all instances there was a deficiency in lysine-ketoglutarate reductase, saccharopine dehydrogenase, and
G Tang et al.
The Plant journal : for cell and molecular biology, 23(2), 195-203 (2000-08-06)
Both plants and animals catabolize lysine via saccharopine by two consecutive enzymes, lysine-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH), which are linked on a single polypeptide. We recently demonstrated that Arabidopsis plants possess not only a bifunctional LKR/SDH but in
C Esmahan et al.
Applied and environmental microbiology, 60(6), 1705-1710 (1994-06-01)
Penicillium chrysogenum L2, a lysine auxotroph blocked in the early steps of the lysine pathway before 2-aminoadipic acid, was able to synthesize penicillin when supplemented with lysine. The amount of penicillin produced increased as the level of lysine in the
V V Rao et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 103(1), 221-224 (1992-09-01)
1. Developmental aspects of L-lysine-ketoglutarate reductase, the first enzyme in saccharopine pathway of L-lysine degradation in rat liver and brain tissues were studied. 2. Although the adult rat brain shows negligible activity, the enzyme activity was shown to be highly
Valeria Fochi et al.
The New phytologist, 213(1), 365-379 (2016-11-20)
Orchids are highly dependent on their mycorrhizal fungal partners for nutrient supply, especially during early developmental stages. In addition to organic carbon, nitrogen (N) is probably a major nutrient transferred to the plant because orchid tissues are highly N-enriched. We

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