S4636
超氧化物歧化酶 来源于辣根
lyophilized powder, 1,000-4,000 units/mg protein
别名:
SOD, 超氧化物:超氧化物氧化还原酶
form
lyophilized powder
specific activity
1,000-4,000 units/mg protein
composition
Protein, ≥70% biuret
storage temp.
−20°C
General description
Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.
Application
Superoxide dismutase from horseradish has been used in a study to assess the correlation between CuZn superoxide dismutase and glutathione reductase, and environmental and xenobiotic stress tolerance in maize inbreds. Superoxide dismutase from horseradish has also been used in a study to investigate chemiluminometric enzyme sensors for flow-injection analysis.
Biochem/physiol Actions
Catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice.
Physical form
含磷酸钾缓冲盐的冻干粉
Analysis Note
关于试验方法请参阅 McCord, J.M. and Fridovich,I., J. Biol. Chem., 244, 6049 (1969)。
Other Notes
One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 °C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Characterisation by EPR spectroscopy of the co-ordination environment of copper in superoxide dismutase from horseradish (Armoracia rusticana Gaertn.)
Palivan, C., et al.
Proceedings of the Royal Society of Edinburgh. Section B: Biology, 102B, 273-277 (1994)
Chemiluminometric enzyme sensors for flow-injection analysis
Spohn, U., et al.
Analytica Chimica Acta, 303, 109-120 (1995)
Correlation between CuZn superoxidedismutase and glutathione reductase, and environmental and xenobiotic stress tolerance in maize inbreds
Malan, C., et al.
Plant Science, 69, 157-166 (1990)
From mice to men: gene therapy's future for treatment of myocardial infarction.
Brian G Kral et al.
Circulation. Cardiovascular imaging, 6(3), 360-362 (2013-05-23)
Jian-Yu Liu et al.
Zhen ci yan jiu = Acupuncture research, 38(1), 48-51 (2013-05-09)
To observe the effect of electroacupuncture (EA) intervention on free radical metabolism in athletes during intensive endurance exercise, so as to reveal its mechanism underlying fatigue relief. Thirty male college student volunteers were equally divided into control group, intensive endurance
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