S5006
L-丝氨酸-O-硫酸酯 钾盐
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关于此项目
线性分子式:
C3H6NO6SK
化学文摘社编号:
分子量:
223.25
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352300
MDL number:
InChI
1S/C3H7NO6S.K/c4-2(3(5)6)1-10-11(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);/q;+1/p-1/t2-;/m0./s1
SMILES string
[K+].N[C@@H](COS([O-])(=O)=O)C(O)=O
InChI key
LXIPCUMLLKNUSU-DKWTVANSSA-M
storage temp.
2-8°C
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Lorraine Brennan et al.
Neurochemistry international, 48(8), 739-745 (2006-02-07)
L-serine-O-sulphate is a member of a group of amino acids collectively called gliotoxins and is a substrate for the high affinity sodium-dependent glutamate transporters. Previous studies have shown that it is toxic to primary cultures of astrocytes but the mode
Crystallographic and chemical studies on cytosolic aspartate aminotransferase.
A Arnone et al.
Progress in clinical and biological research, 144B, 171-193 (1984-01-01)
Elena Fumagalli et al.
European journal of pharmacology, 578(2-3), 171-176 (2007-11-27)
Riluzole exerts a neuroprotective effect through different mechanisms, including action on glutamatergic transmission. We investigated whether this drug affects glutamate transporter-mediated uptake, using clonal cell lines stably expressing the rat glutamate transporters GLAST, GLT1 or EAAC1. We found that riluzole
A novel reaction of the coenzyme of glutamate decarboxylase with L-serine O-sulfate.
J J Likos et al.
Biochemistry, 21(18), 4377-4386 (1982-08-31)
R J Vandenberg et al.
British journal of pharmacology, 123(8), 1593-1600 (1998-05-30)
1. Expression of the recombinant human excitatory amino aid transporters, EAAT1 and EAAT2, in Xenopus laevis oocytes allows electrogenic transport to be studied under voltage clamp conditions. 2. We have investigated the transport of the pharmacological substrate, L-serine-O-sulphate transport by
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