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About This Item
经验公式（希尔记法）:
C12H10Cl2N2O5PSNa
CAS Number:
分子量:
419.15
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
方案
≥98% (HPLC)
表单
solid
颜色
white
溶解性
H2O: 1 mM
DMSO: freely soluble
ethanol: freely soluble
运输
dry ice
储存温度
−70°C
SMILES字符串
[Na+].O[C@@H]1[C@@H]2O[P@]([S-])(=O)OC[C@H]2O[C@H]1n3cnc4cc(Cl)c(Cl)cc34
应用
Sp 5,6-DCl-cBIMPS may be used in cAMP-dependent protein kinase-mediated cell signaling studies.
生化/生理作用
Selective cAMP-dependent protein kinase (PKA) activator. Especially suitable for intact cells showing preference for site B of type II isozyme. Completely stable against mammalian cPDE types I & III and only extremely slowly hydrolized by cPDE type II. Surpasses the widely used but problematic dibutyryl cAMP or 8-CPT-cAMP in terms of metabolic stability, membrane permeability and potency.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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