S8076
SJ000025081
≥98% (HPLC)
别名:
7-(3,4-Dimethoxyphenyl)-4-(2-fluorophenyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-3-quinolinecarboxylic acid propyl ester
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C28H30FNO5
化学文摘社编号:
分子量:
479.54
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C28H30FNO5/c1-5-12-35-28(32)25-16(2)30-21-13-18(17-10-11-23(33-3)24(15-17)34-4)14-22(31)27(21)26(25)19-8-6-7-9-20(19)29/h6-11,15,18,26,30H,5,12-14H2,1-4H3
SMILES string
CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3F)C(=O)CC(C2)c4ccc(OC)c(OC)c4
InChI key
JYAOIVVCGRSAFZ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
pale yellow
solubility
DMSO: ≥40 mg/mL
storage temp.
2-8°C
Application
SJ000025081 may be used in studies related to malarial parasite and immune signaling.
Biochem/physiol Actions
SJ000025081 is an antimalarial compound that inhibit the growth of asexual blood-stage P. falciparum in cultured red blood cells.
SJ000025081 is an antimalarial compound.
SJ000025081 is a dihydropyridine effective against Plasmodium yoelii.1,2
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Brian T Grimberg et al.
Pharmaceuticals (Basel, Switzerland), 4(5), 681-712 (2011-06-01)
The number of available and effective antimalarial drugs is quickly dwindling. This is mainly because a number of drug resistance-associated mutations in malaria parasite genes, such as crt, mdr1, dhfr/dhps, and others, have led to widespread resistance to all known
W Armand Guiguemde et al.
Chemistry & biology, 19(1), 116-129 (2012-01-31)
Malaria, a devastating infectious disease caused by Plasmodium spp., leads to roughly 655,000 deaths per year, mostly of African children. To compound the problem, drug resistance has emerged to all classical antimalarials and may be emerging for artemisinin-based combination therapies.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持