生物来源
Porcine
质量水平
无菌性
non-sterile
表单
powder
分子量
~22 kDa
包装
vial of ~50 IU
drug control
Home Office Schedule 4.2
溶解性
ethanolamine: 5 mg/mL (basic buffers, pH 9-10)
UniProt登记号
运输
ambient
储存温度
2-8°C
基因信息
pig ... GH(396884)
Amino Acid Sequence
Phe-Pro-Ala-Met-Pro-Leu-Ser-Ser-Leu-Phe-Ala-Asn-Ala-Val-Leu-Arg-Ala-Gln-His-Leu-His-Gln-Leu-Ala-Ala-Asp-Thr-Tyr-Lys-Glu-Phe-Glu-Arg-Ala-Tyr-Ile-Pro-Glu-Gly-Gln-Arg-Tyr-Ser-Ile-Gln-Asn-Ala-Gln-Ala-Ala-Phe-Cys-Phe-Ser-Glu-Thr-Ile-Pro-Ala-Pro-Thr-Gly-Lys-Asp-Glu-Ala-Gln-Gln-Arg-Ser-Asp-Val-Glu-Leu-Leu-Arg-Phe-Ser-Leu-Leu-Leu-Ile-Gln-Ser-Trp-Leu-Gly-Pro-Val-Gln-Phe-Leu-Ser-Arg-Val-Phe-Thr-Asn-Ser-Leu-Val-Phe-Gly-Thr-Ser-Asp-Arg-Val-Tyr-Glu-Lys-Leu-Lys-Asp-Leu-Glu-Glu-Gly-Ile-Gln-Ala-Leu-Met-Arg-Glu-Leu-Glu-Asp-Gly-Ser-Pro-Arg-Ala-Gly-Gln-Ile-Leu-Lys-Gln-Thr-Tyr-Asp-Lys-Phe-Asp-Thr-Asn-Leu-Arg-Ser-Asp-Asp-Ala-Leu-Leu-Lys-Asn-Tyr-Gly-Leu-Leu-Ser-Cys-Phe-Lys-Lys-Asp-Leu-His-Lys-Ala-Glu-Thr-Tyr-Leu-Arg-Val-Met-Lys-Cys-Arg-Arg-Phe-Val-Glu-Ser-Ser-Cys-Ala-Phe
一般描述
Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.
应用
Somatotropin (STH) has been used to study its effects on repressing hepatic H2S production post-transcriptionally. It has also been used as one of the components of a medium to culture primordial follicles.
生化/生理作用
Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Stijn J M Niessen et al.
The Veterinary clinics of North America. Small animal practice, 43(2), 319-350 (2013-03-26)
When confronted with a diabetic cat in clinical practice, it is tempting to assume it has a form of diabetes mellitus akin to human type 2 diabetes mellitus (diabetes). For most diabetic cats examined, this will indeed be justified. Nevertheless
Obesity: a somatotrope perspective.
Buffy S Ellsworth
Endocrinology, 154(4), 1390-1391 (2013-03-26)
Manuel D Gahete et al.
Endocrinology, 154(7), 2410-2420 (2013-05-15)
IGF-I is considered a primary inhibitor of GH secretion. Insulin may also play an important role in regulating GH levels because insulin, like IGF-I, can suppress GH synthesis and release in primary pituitary cell cultures and insulin is negatively correlated
Ying Liu et al.
BMC biotechnology, 13, 21-21 (2013-03-19)
Distinguishing desired mutants from parental templates and undesired mutants is a problem not well solved in Quikchange™ mutagenesis. Although Dpn I digestion can eliminate methylated parental (WT) DNA, the efficiency is not satisfying due to the existence of hemi-methylated DNA
Somatotropin in the treatment of growth hormone deficiency and Turner syndrome in pediatric patients: a review
Clinical Pharmacology and Therapeutics (2010)
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