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S9132

螺旋霉素

Name: 螺旋霉素
Brand: SIGMA

别名:

Rovamycin, Formacidine

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关于此项目

化学文摘社编号:

8025-81-8

NACRES:

NA.85

PubChem Substance ID:

24899826

UNSPSC Code:

51283208

EC Number:

232-429-6

MDL number:

MFCD01314545

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属性

form

powder

Quality Segment

200

optical activity

[α]/D -85 to -80° in water (Specific rotation (dry basis))

potency

≥4100 I.U. per mg (dry basis)

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

color

white to light yellow

solubility

methanol: soluble

cation traces

heavy metals: ≤20 ppm

antibiotic activity spectrum

Gram-positive bacteria

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C

InChI

1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1

InChI key

ACTOXUHEUCPTEW-JMRHEKERSA-N

说明

General description

Chemical structure: macrolide

Application

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

Biochem/physiol Actions

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

Analysis Note

A mixture of Spiramycin I, II and III.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c