S9511
超氧化物歧化酶 来源于狗红细胞
lyophilized powder, 2,000-6,000 units/mg protein
别名:
SOD, 超氧化物:超氧化物氧化还原酶
form
lyophilized powder
specific activity
2,000-6,000 units/mg protein
mol wt
~31,200 (two identical subunits)
composition
Protein, ≥90% biuret
UniProt accession no.
storage temp.
−20°C
Gene Information
dog ... SOD1(403559)
Biochem/physiol Actions
Catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby promoting the activity of NO.1 SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines and transgenic mice.2,3
Physical form
含磷酸钾缓冲盐的冻干粉
Analysis Note
For assay method, see McCord, J.M. and Fridovich,I., J. Biol. Chem., 244, 6049 (1969).
Other Notes
One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 °C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Bovine erythrocyte superoxide dismutase. Complete amino acid sequence.
H M Steinman et al.
The Journal of biological chemistry, 249(22), 7326-7338 (1974-11-25)
From mice to men: gene therapy's future for treatment of myocardial infarction.
Brian G Kral et al.
Circulation. Cardiovascular imaging, 6(3), 360-362 (2013-05-23)
Jian-Yu Liu et al.
Zhen ci yan jiu = Acupuncture research, 38(1), 48-51 (2013-05-09)
To observe the effect of electroacupuncture (EA) intervention on free radical metabolism in athletes during intensive endurance exercise, so as to reveal its mechanism underlying fatigue relief. Thirty male college student volunteers were equally divided into control group, intensive endurance
Raymond S W Tsang et al.
Canadian journal of microbiology, 59(5), 362-364 (2013-05-08)
Haemophilus influenzae serotype a (Hia) is an important pathogen since the introduction of vaccines for control of disease due to serotype b strains. Using a sodC-based polymerase chain reaction, Hia can be divided into 2 phylogenetic divisions, each with their
Guogui Sun et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 34(3), 1409-1419 (2013-05-08)
Manganese superoxide dismutase (MnSOD) catalyzes superoxide radical (O2 (-)) into hydrogen peroxide (H2O2), which is further catalyzed by the combined action of glutathione peroxidase (GPx) and catalase (CAT) into water and oxygen. MnSOD plays a role in cell protection from
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