S9882
磺胺氯哒嗪
别名:
4-氨基- N -（6-氯-3-哒嗪基）苯磺酰胺, N 1 -（6-氯-3-哒嗪基）磺胺
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H9ClN4O2S
化学文摘社编号:
分子量:
284.72
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
201-269-9
Beilstein/REAXYS Number:
261558
MDL number:
InChI key
XOXHILFPRYWFOD-UHFFFAOYSA-N
InChI
1S/C10H9ClN4O2S/c11-9-5-6-10(14-13-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)
SMILES string
Nc1ccc(cc1)S(=O)(=O)Nc2ccc(Cl)nn2
form
powder
color
off-white to light yellow
solubility
0.5 M NaOH: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycoplasma
mode of action
DNA synthesis | interferes
正在寻找类似产品? 访问 产品对比指南
Application
磺胺氯哒嗪是一种磺胺类抗生素，用于研究动力学、反应途径和毒性演变 。磺胺氯哒嗪已被用于治疗儿科患者的急性尿路感染 。
Biochem/physiol Actions
磺胺氯哒嗪是一种磺胺类抗生素，通过抑制二氢丙酸合成酶来阻断二氢叶酸的合成。磺胺氯哒嗪是细菌对氨基苯甲酸（PABA）的竞争性抑制剂，它是细菌合成叶酸所必需的。它对革兰氏阳性细菌、革兰氏阴性细菌和衣原体均具有抗性。抗性产生机制是通过改变二氢蝶酸合成酶或叶酸合成的替代途径。
Other Notes
保存于密闭容器内，置于干燥通风处。
Absorption and Excretion of Sulfachloropyridazine
Wilfred F. Jones, Jr, Mohsen Ziai, et al.
Exp. Biol. Med, 95, 642-645 (1957)
[Sulfachloropyridazine in the treatment of acute infections of the urinary tract in childhood].
R C PEDRINAZZI et al.
Minerva pediatrica, 12, 1342-1347 (1960-10-27)
Thomas L ter Laak et al.
Environmental toxicology and chemistry, 25(4), 904-911 (2006-04-25)
Antimicrobial agents are the most heavily used pharmaceuticals in intensive husbandry. Their usual discharge pathway is application to agricultural land as constituents of animal manure, which is used as fertilizer. Many of these compounds undergo pH-dependent speciation and, therefore, might
Paul A Blackwell et al.
Chemosphere, 67(2), 292-299 (2007-01-06)
The environmental fate of the antibiotics sulfachloropyridazine and oxytetracycline was investigated in a sandy loam soil. Liquid pig manure was fortified with the compounds and then applied to soil plots to investigate leaching, dissipation and surface run-off under field conditions.
Paul Kay et al.
Environmental toxicology and chemistry, 23(5), 1136-1144 (2004-06-08)
The environment may be exposed to veterinary medicines administered to livestock through the application of organic fertilizers to land. For other groups of substances that are applied to agricultural land (e.g., pesticides), preferential flow in underdrained clay soils has been
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持