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Merck
CN

SAB1300003

Sigma-Aldrich

Monoclonal Anti-SET07 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

别名:

Anti-H4-K20-HMTase, Anti-Histone H4-K20 methyltransferase, Anti-PR/SET07, PR/SET domain-containing protein 07, SET domain-containing protein 8

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

43AT551.86, monoclonal

表单

buffered aqueous solution

种属反应性

mouse, human

技术

indirect ELISA: 1:1000
western blot: 1:100-1:500

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... SET07(387893)

一般描述

SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.

免疫原

SET07 (AAF97812, N Terminal)
This antibody was raised using purified recombinant GST fusion protein encoding the N-terminal region of human SET07.

外形

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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