SAB1300146
Anti-UBA2 (N-term) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
别名:
Anti-HRIHFB2115, Anti-SUMO-1 activating enzyme subunit 2, Anti-Ubiquitin-like 2 activating enzyme E1B, Anthracycline-associated resistance ARX
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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
indirect ELISA
western blot
indirect ELISA
western blot
Species reactivity:
human, mouse
Citations:
Technique(s):
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
indirect ELISA: 1:1000
western blot: 1:100-1:500
Uniprot accession no.:
产品名称
Anti-UBA2 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, mouse
technique(s)
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... UBA2(10054)
General description
Ubiquitin is covalently attached to target proteins by a multienzymatic system consisting of E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-ligating) enzymes. NEDD8, a ubiquitin-like protein, is conjugated to proteins in a manner analogous to ubiquitinylation. beta-amyloid precursor protein-binding protein-1 (APPBP1) can bind to NEDD8 in rabbit reticulocyte lysates. However, since APPBP1 shows similarity to only the N-terminal domain of an E1 enzyme, it must interact with a protein showing similarity to the C-terminal region of E1s. By searching sequence databases, a cDNAs encoding UBA3 was identified as the human homolog of yeast Uba3. The predicted 442-amino acid UBA3 protein shares 43% sequence identity with yeast Uba3. In vitro, UBA3 formed a complex with APPBP1 and a thioester linkage with NEDD8. APPBP1/UBA3 complex may function as an E1-like enzyme for the activation of NEDD8.
Immunogen
UBA2 (Q9UBT2, 1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBA2.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBA2.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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