SAB1306537
ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, mouse
Application:
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Technique(s):
flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:1000
Citations:
12
Uniprot accession no.:
产品名称
ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
51896 Da
species reactivity
human, mouse
technique(s)
flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BECN1(8678)
Application
ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit has been used in Western blotting.
Biochem/physiol Actions
Beclin 1 (BECN1) acts as an initiator of autophagy and is vital in the early stages of autophagosome formation. It has a role in various tumors and cancers. BECN1 is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Beclin 1 (BECN1) is a tumor suppressor gene. It is a 450 amino-acid protein having three domains. The gene encoding BECN1 is localized on human chromosome 17q21.
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Polyglutamine tracts regulate beclin 1-dependent autophagy.
Ashkenazi A, et al.
Nature, 545, 108-111 (2017)
Class III phosphoinositide 3-kinase?Beclin1 complex mediates the amino
acid-dependent regulation of autophagy in C2C12 myotubes
acid-dependent regulation of autophagy in C2C12 myotubes
BioChemistry: An Indian Journal (2003)
Role of Autophagy in Breast Cancer
Vassiliki Karantza & Eileen White
Autophagy (2007)
RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-?-Catenin Pathway in Glutamate Excitotoxicity Injury
Yuefan Yang
Frontiers in Cellular Neuroscience (2017)
Decreased expression of Beclin?1 is significantly associated with a poor prognosis in oral tongue squamous cell carcinoma.
Hu Z
Molecular Medicine Reports, 14(2), 1567-1573 (2016)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持