SAB1405428
Anti-ADFP antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
别名:
ADRP, MGC10598
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~48.1 kDa
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ADFP(123)
General description
Adipocyte differentiation-related protein is associated with the globule surface membrane material. This protein is a major constituent of the globule surface. Increase in mRNA levels is one of the earliest indications of adipocyte differentiation (provided by RefSeq)
Adipose differentiation-related protein (ADRP), also known as adipose differentiation-related protein (ADFP), is the major lipid droplet protein. It is encoded by the gene mapped to human chromosome 9p22.1–p21.3. ADFP is ubiquitously expressed and is a member of PAT (perilipin/APRP/TIP47) family.
Immunogen
ADFP (NP_001113.2, 1 a.a. ~ 437 a.a) full-length human protein.
Sequence
MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH
Sequence
MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH
Biochem/physiol Actions
Adipose differentiation-related protein (ADFP) plays a vital role in lipid droplet (LD) formation and/or maturation. Increased expression of this protein in tamm-horsfall protein 1 (THP-1) macrophages increases lipid accumulation and stops lipid efflux. In addition, ADFP is slightly involved in maintenance of adipose tissue homeostasis. It acts as a potential marker for intracellular LD in tissues.
Physical form
Solution in phosphate buffered saline, pH 7.4
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Identification of differentially expressed genes in omental adipose tissues of obese patients by suppression subtractive hybridization
Qiu J, et al.
Biochemical and Biophysical Research Communications, 352(2), 469-478 (2007)
Functional Compensation for Adipose Differentiation-related Protein (ADFP) by Tip47 in an ADFP Null Embryonic Cell Line
Sztalryd C, et al.
The Journal of Biological Chemistry, 281(45), 34341-34348 (2006)
Regulation of Triglyceride Metabolism. III. Emerging role of lipid droplet protein ADFP in health and disease
Chang BHJ, et al.
The American Journal of Physiology, 292(6), G1465-G1468 (2007)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持