biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
50 kDa
species reactivity
rat, human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RNH1(6050)
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General description
Ribonuclease/angiogenin inhibitor 1 (RNH1) is a cytoplasmic protein ubiquitously produced in all organs except testis. Rnh1 was first isolated from human placenta. The gene RNH1 is located in the human chromosome on 11p15.5.
Immunogen
Synthetic peptide directed towards the middle region of human RNH1
Biochem/physiol Actions
Ribonuclease/angiogenin inhibitor 1 (RNH1) has several leucine rich repeats which aids them in protein-protein interaction. Rnh1 binds with greater affinity and reversibly to members of ribonuclease 1 (RNase 1). Rnh1 has high affinity to angiogenin and inhibits its angiogenic functionality.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: LLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEG
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Three decades of research on angiogenin: a review and perspective
Sheng J and Xu Z
Acta biochimica et biophysica Sinica, 48(5), 399-410 (2015)
Isolation and expression analysis of the human RNH2 gene encoding ribonuclease inhibitor 2
Miyamoto T and Hasuike S
Journal of Assisted Reproduction and Genetics, 19(8), 394-397 (2002)
An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract
Spencer JD, et al.
Kidney International, 85(5), 1179-1191 (2014)
A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci.
Richard 3rd CW, et al.
American Journal of Human Genetics, 52(5), 915-921 (1993)
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