Anti-BCL11B antibody produced in rabbit

Synthetic peptide directed towards the middle region of human BCL11B

BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Synthetic peptide located within the following region: QASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELAGEGLKAADG

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