SAB2500530
Anti-IFT88/Polaris antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-D13S1056E, Anti-HGNC:20606, Anti-Polaris, Anti-TTC10, Anti-Tetratricopeptide repeat domain 10
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC
Citations:
4
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human
technique(s)
ELISA: suitable, immunofluorescence: suitable, immunohistochemistry: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IFT88(8100)
General description
Intraflagellar transport 88 (IFT88) is a liver tumor suppressor gene. It consists of 824 amino acids and possesses tetratricopeptide repeats.
Immunogen
Peptide with sequence C-KKRIDEDDFADEE from the C Terminus of the protein sequence according to NP_783195.2; NP_006522.2.
Biochem/physiol Actions
Intraflagellar transport 88 (IFT88) is involved in cilia formation. It is linked to polycystic kidney disease. In mitosis, the protein has a crucial role in spindle orientation. IFT88 is downregulated in hepatocellular carcinoma.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Polaris, a Protein Involved in Left-Right Axis Patterning, Localizes to Basal Bodies and Cilia
Patrick D
Molecular Biology of the Cell (2001)
The cilia protein IFT88 is required for spindle orientation in mitosis.
Delaval B
Nature Cell Biology (2011)
Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells.
You N
Journal of Experimental & Clinical Cancer Research (2012)
The molecular biology of polycystic kidney disease
Noel S
Pediatric Nephrology (Berlin) (1998)
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