SAB2500750
Anti-PARK7/DJ-1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-DJ1, Anti-Oncogene DJ1, Anti-Parkinson disease (autosomal recessive)
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
6
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, mouse, human
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PARK7(11315)
Immunogen
Peptide with sequence C-AAQVKAPLVLKD from the C Terminus of the protein sequence according to NP_009193.
Application
Anti-PARK7/DJ-1 antibody produced in goat is suitable for indirect ELISA and western blot.
Biochem/physiol Actions
PARK7 is a member of novel glyoxalase family. It exerts mitochondrial activity. It has been suggested that PARK7 may act as an antioxidant and/or a molecular chaperone. It may also detoxify aggressive metabolic aldehyde by-products. It helps in stabilizing mitochondria during cellular stress. Alteration in gene function affects neurodegeneration, which leads to the autosomal recessive early-onset parkinsonism.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Larissa Berloffa Belardin et al.
Journal of assisted reproduction and genetics, 33(12), 1657-1664 (2016-09-16)
To verify if the presence of varicocele (grades II and III) with and without seminal alterations, using the 5 This cross sectional study was performed at the Sao Paulo Federal University Paulo between May 2014 and April 2016. A total
V Bonifati et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 24(3), 159-160 (2003-11-05)
Four chromosomal loci ( PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. We mapped the PARK7 locus to chromosome 1p36 in a large family from a genetically isolated population in the Netherlands, and confirmed
Vincenzo Bonifati et al.
Science (New York, N.Y.), 299(5604), 256-259 (2002-11-26)
The DJ-1 gene encodes a ubiquitous, highly conserved protein. Here, we show that DJ-1 mutations are associated with PARK7, a monogenic form of human parkinsonism. The function of the DJ-1 protein remains unknown, but evidence suggests its involvement in the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB2500750-100UG | 04061832485300 |