biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, mouse
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
mouse ... Itga11(319480)
General description
Integrin subunit α 11 (ITGA11) is expressed in stromal fibroblasts. Together with the integrin subunit β, it forms a receptor for collagen.
Immunogen
Peptide with sequence PTEEDLSHAPQRNH, from the internal region (near C-terminus) of the protein sequence according to NP_795896.4
Biochem/physiol Actions
Integrin subunit α 11 (ITGA11) may have a role in the organization of interstitial collagen matrices. It has been shown to be upregulated in non-small-cell lung carcinoma. Mice, which are deficient in ITGA11, exhibit signs of dwarfism and malnutrition.
Features and Benefits
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Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
a11?1 Integrin-Dependent Regulation of Periodontal Ligament Function in the Erupting Mouse Incisor
Svetlana N
Molecular and Cellular Biology (2007)
Integrin a11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells
Chang-Qi Zhu
Proceedings of the National Academy of Sciences of the USA (2007)
alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells.
Tiger CF
Developmental Biology (2001)
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