SAB2501718
Anti-COPS3 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
COP9 complex subunit 3, COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis), CSN3, SGN3
生物来源
goat
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human, canine, mouse, rat, bovine
技术
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... COPS3(8533)
一般描述
COPS3 (COP9 signalosome subunit 3) encodes the third subunit of an eight-subunit complex, the COP9 signalosome (CSN), and is located on chromosome 17p11.2.
免疫原
Peptide with sequence C-SLYKKNIQRLT, from the internal region of the protein sequence according toNP_003644.2
应用
Anti-COPS3 antibody produced in goat is suitable for indirect ELISA and western blot applications.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Inhibition of Csn3 expression induces growth arrest and apoptosis of hepatocellular carcinoma cells.
Yong-sheng Yu et al.
Cancer chemotherapy and pharmacology, 69(5), 1173-1180 (2012-01-13)
Csn3 (or CSN3) encodes the third subunit of an eight-subunit complex, the COP9 signalosome (CSN), which acts as a protein kinase and a deneddylase in mammalian cells. Previous studies have shown that Csn3 is essential for maintenance of cell proliferation
Joeri Both et al.
PloS one, 7(1), e30907-e30907 (2012-02-01)
Osteosarcoma is the most common primary malignancy of bone. The tumours are characterized by high genomic instability, including the occurrence of multiple regions of amplifications and deletions. Chromosome region 17p11.2-p12 is amplified in about 25% of cases. In previous studies
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