Anti-Gli1 antibody produced in rabbit

GLI-Kruppel family member Gli1 is a transcriptional activator, which is part of the Gli family of transcription factors. It is a target of hedgehog signaling.

Synthetic peptide containing a sequence corresponding to a region within amino acids 755 and 810 of Gli1 according to NP_034426

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

GLI-Kruppel family member Gli1 may regulate the transcription of specific genes during normal development. It may also play a role in osteoblast formation, craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. The protein mediates SHH signaling and thus cell proliferation and differentiation. Gli1 may also be involved in tissue repair in pancreas. This protein has a protective role during stroke, ischemic injury and Parkinson′s disease.

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1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

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