产品名称
Monoclonal Anti-Dengue virus Envelope protein antibody produced in mouse, clone GT643, affinity isolated antibody
biological source
mouse
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
GT643, monoclonal
form
buffered aqueous solution
mol wt
51-60kDa
species reactivity
Dengue virus
concentration
1mg/mL
technique(s)
flow cytometry: suitable
immunofluorescence: 1:100-1:2,000
western blot: 1:500-1:3,000
isotype
IgG2b
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:2000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Dengue virus is an arthropod borne flavivirus. Dengue virus (DENV) is a human pathogen, known to cause one of the major illness, dengue fever (DF) in humans. DENV belongs to the Flaviviridae family. The virus attaches and enters the host cell with the help of a major envelope protein glycoprotein, E. The dengue envelope protein sequence consists of two putative glycosaminoglycan-binding motifs at the carboxy terminus.
Immunogen
Recombinant protein encompassing a sequence within the center region of Dengue virus Envelope protein.
Other Notes
Purification: Affinity purified by Protein G
Physical form
Phosphate-buffered saline, no preservative added.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Type-and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes.
Sukupolvi-Petty S, et al.
Journal of Virology, 81(23), 12816-12826 (2007)
A ligand-binding pocket in the dengue virus envelope glycoprotein.
Modis Y, et al.
Proceedings of the National Academy of Sciences of the USA, 100(12), 6986-6991 (2003)
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate.
Chen Y, et al.
Nature Medicine, 3(8), 866-866 (1997)
Ankit Kumar et al.
Asian journal of transfusion science, 16(1), 67-72 (2022-10-07)
The study objective was evaluation of amotosalen and ultraviolet A (UVA) illumination-based inactivation of dengue virus (DENV) in blood platelets. Whole blood was collected from healthy donors and platelet concentrates were prepared at a tertiary care hospital in Gurugram, India.
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