Anti-GPR4 antibody produced in rabbit

Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR4. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Dog, Panda, Pig (100%); Bovine, Bat, Rabbit, Zebrafish (95%); Mouse, Rat (85%).

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Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Supplied at 1 mg/ml

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